Effect of acetone fraction of leaf extract of Simarouba glauca DC. on mitotic cells of Allium cepa L.

Binu Thomas

Effect of acetone fraction of leaf extract of Simarouba glauca DC. on mitotic cells of Allium cepa L.

Keywords : Acetone fraction, Simarauba glauca DC., mitotic cells, Allium cepa L.


Abstract

The present study is an attempt to evaluate the effect of acetone fraction of Simarauba glauca DC. leaf extract on mitotic cells of Allium cepa L. The extract of S. glauca leaves decreased mitotic index of A. cepa L. cells at all the test concentrations. It was observed that extract induces mitotic aberrations, including stickiness, disorientation and tropokinesis. Tropokinesis at anaphase and telophase were frequent. The aberrations confirmed the presence of an active principle in the fraction and having significant influence on spindle apparatus. Thus there is a strong support in the light of the study towards the use of low concentration of this plant extract may reduce any ailment that involves uncontrolled cell division.

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