Nature has been a source of medicinal agents for thousands of years and a large number of modern drugs have been derived from natural sources. The medicinal plant industry is posing great threat due to the unavailability of genuine raw drugs thereby resulting in the use of several substitutes / adulterants as the source plant. In the near future, many species may be totally unavailable for the use of industry due to over exploitation. Solvent extraction is most frequently used technique for isolation of plant metabolites. However, the extract yields of the plant materials are strongly depend on the nature of extracting solvent, due to the different solubility of the chemical compounds present in it. Identification of most effective extraction solvents to increase the yield of raw materials is of great importance as it helps reducing the quantity required for medicine manufacture. Salacia, one among the over exploited medicinally valuable plant and many of its species are proven to be anti-diabetic. Salacia fruticosa Wall. One of the red listed medicinal plants belonging to the family Celastraceae is selected. In the present study the effect of extraction solvents on phytochemicals of various parts of Salacia fruticosa (root, stem, leaves) using various chromatographic techniques like HPTLC and HPLC is evaluated. HPLC studies revealed substantial variation in terms of phytoconstituents.
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