Effects of Paracetamol (Acetaminophen) Usage on Sperm Count
- Author Sulaimon Mutiu O.
- Co-Author Adewunmi Olusola A., Mabosanyinje Adedeji, Adewunmi Adebisi R.
- DOI
- Country : Nigeria
- Subject : Statistics & Mathematics
Keywords : Count, Effect, Paracetamol, Sperm, Usage
Abstract
Several published studies have connected paracetamol (also named Acetaminophen, a commonly used analgesic and antipyretic medication) with semen quality and male fertility. This research work statistically investigates the effects of paracetamol usage on sperm count by modelling the impact of varieties of paracetamol combinations, different dosage of varieties of paracetamol combinations and the interactions on sperm count. Data for this research was collected primarily via experimental method. A sample of 30 adult male albino rats weighing 160g – 180g was used in lieu of human beings to determine the effect of paracetamol on sperm count. Sperm extraction were carried out after the completion of the expected drug administration period to determine the available sperm count for each rat which were thereafter analysed statistically to make appropriate inferences. One of the results from the findings shows that rats administered 500mg of Orphensic with basal feed approximately produce the least sperm count of 7.500 million on the average. The varieties of paracetamol combinations significantly have different effects on sperm count. Of the ten interactions, significant interaction effects on sperm count is found in 500mg of Standard paracetamol, 500mg of Cenpain, 1000mg of Standard paracetamol and 1000mg of Cenpain. More also, long term paracetamol usage does not reduce body weight. We advise that men especially should be careful in acetaminophen usage without the prescription of their physician. They should be conscious of the level of consumption of parcetamol as it does significantly affect sperm count in general.
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