Recent advances in treatment of Triple-negative breast cancer
- Author Dr. Himanshu Gupta
- Co-Author Dr. Amiya
- DOI http://wwj
- Country : India
- Subject : Pharmacology
Keywords : Breast cancer, human epidermal growth factor receptor 2, poly (ADP-ribose) polymerase inhibitor, programmed cell death protein 1, triple negative breast cancer
Abstract
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high invasiveness, high metastatic potential, high risk of relapse, and poor prognosis. Because TNBC tumors lack ER, PR, and HER2 expression, they are not sensitive to endocrine therapy or HER2 treatment, and standardized TNBC treatment regimens are still lacking. Therefore, development of new TNBC treatment strategies has become an urgent clinical need. This paper aims to provide recent treatment options and their future prospects for TNBC treatment.
Comments
No have any comment !