Prognostic Significance of Il-6 in Women with Antenatal Fetal Death during Covid-19 Pandemic
- Author Pkhaladze N
- Co-Author Kintraia N, Gogokhia N, Mikaberidze K, Didbaridze T
- DOI 10.17605/O
- Country : Georgia
- Subject : Obstetrics and Gynecology
Keywords : IL-6, pregnancy, IFA, SARS cov2
Abstract
The proinflammatory cytokine IL-6 was studied by the method of immune-ferment analysis (IFA) in the blood serum in women with antenatal fetal death during covid infection. 3 patients suffering from this complication were examined (the principal group) and 25 patients - of adequate age groups and gestation periods but live fetuses in both groups presented SARS cov 2 infection which was confirmed with laboratory PCR (Polymerase Chain Reaction) test. The result of studies showed that the content of proinflammatory cytokine IL-6 in women with antenatal fetal death was significantly higer in the blood than in patients with normal progress of pregnancy. The obtained data prove that further studies of cytokine profile and especially of IL-6 may become an important method for the prognosis for antenatal fetal death, during SARS Cov 2 pandemic period.
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