In-Vitro Evaluation of Anti- Alzheimer Activity of Alternanthera brasiliana Leaf Extract
- Author Riyama Shirin V. K
- Co-Author Dr. Arthi. I
- DOI https://ww
- Country : India
- Subject : Pharmacognosy and Phytochemistry
Keywords : Alternanthera brasiliana, Neurodegeneration, Anti-Alzheimer effect, traditional medicine.
Abstract
Being a medicinal plant, Alternanthera brasiliana plant also known as Brazilian joyweed is known for the treatment of various ailments in traditional medicine. The current study was carried out to analyse the anti-Alzheimer’s potential of ethanolic extract of Alternanthera brasiliana. For this inhibition of beta amyloid induced neurodegeneration was determined by MTT Assay and acetylcholinesterase inhibition potential of Alternanthera brasiliana leaf was evaluated. Anti-lipid peroxidative effect of the extract was also determined by lipid peroxidation cell line assay. The plant has shown neuroprotective effect, significant acetylcholinesterase inhibitory activity and good antioxidant activity. Thus, plant offers to be important source of bioactive constituents for neurodegenerative disease.
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