A Study on Prevalence & Drug Susceptibility Pattern of Newly Diagnosed Pulmonary Tuberculosis Patients in A Tertiary Care Hospital

Brindha.V

A Study on Prevalence & Drug Susceptibility Pattern of Newly Diagnosed Pulmonary Tuberculosis Patients in A Tertiary Care Hospital

Keywords : Drug susceptibility test, INH resistance, MDR-TB, Multi-drug resistant.


Abstract

Purpose: A lot of effort has been put to eradicate Tuberculosis for which diagnosing muti-drug resistant cases early and treating them are of utmost importance. The knowledge of the prevalence and pattern of drug susceptibility helps in formulating ideal protocol for disease eradication.
Methods: The present study is a prospective observational study conducted for a period of 8 months from February 2015 to September 2015 in a total of 887 samples collected from suspected cases of primary pulmonary tuberculosis in a tertiary care hospital.
Results: A total of 78 culture positive samples were obtained from 767 samples contributing 10.16%. Biochemical examination for confirmation of Mycobacterium tuberculosis species was done. Drug susceptibility tests by MGIT 960 method revealed 2 cases of multi-drug resistant tuberculosis.
Conclusion: The prevalence of multi-drug resistance was found to be 2.56%. Only resistance to Rifampicin and Isoniazid was noted in the study group.

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